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Home > Médica Sur Clinic Foundation > Teaching > Colegio de Profesores > Maestrías y Doctorados > Dr. Roberto Medina Santillán

Dr. Roberto Medina Santillán

Para actualizar su información contáctenos portalms@medicasur.org.mx

Coordinador de Maestrías y Doctorados

Departamento: Dirección Académica

Universidad o Facultad: Facultad de Medicina - Universidad Nacional Autónoma de México

Internado Médico: Hospital de la Secretaría de Hacienda y Crédito Público

Certificaciones: 

  • Maestro en Ciencias con especialidad en Bioquímica. Escuela Nacional de Biológicas (IPN).
  • Doctorado en Ciencias con especialidad en Investigación en Medicina (IPN).
  • Post Doctoral Training in Experimental Medicine Tulane. University New Orleans Louisiana, Estados Unidos de Norte América.

Áreas de interés: Complicaciones cardiometabólicas de la diabetes y síndrome metabólico

Contacto: rmedinas@medicasur.org.mx

 
Conozca las publicaciones de
Roberto Medina Santillán
  • Plancarte R, Guajardo-Rosas J, Reyes-Chiquete D, Chejne-Gómez F, Plancarte A, González-Buendía NI, Cerezo-Camacho O, Lee A, Medina-Santillan R. “Management of chronic upper abdominal pain in cancer: transdiscal blockade of the splanchnic nerves”. Reg Anesth Pain Med. Nov;35(6):500-6. 2010.
  • Jacques-Camarena, O., González-Ortiz, M., Martínez-Abundis, E., López-Madrueño, J.F.P., Medina-Santillán, R. “Effect of vanadium on insulin sensitivity in patients with impaired glucose tolerance”. Annals of Nutrition and Metabolism 53 (3-4), pp. 195-198, 2009.
  • Rubio-Guerra, A.F., Vargas-Robles, H., Medina-Santillán, R., Escalante-Acosta, B.A.. “Levels of soluble adhesion molecules among normotensive and hypertensive type 2 diabetic patients [Niveles de moléculas de adhesión solubles en pacientes diabéticos tipo 2 normotensos e hipertensos]”. Gaceta Medica de Mexico, 144, Issue 1, Pages 11-14. 2008.
  • Chávez-Tapia NN, Uribe M, Ponciano-Rodríguez G, Medina-Santillán R, Méndez-Sánchez N. “New insights into the pathophysiology of nonalcoholic fatty liver disease.” Ann Hepatol. 8 Suppl 1:S9-17. 2009.
  • Uribe, M., Zamora-Valdés, D., Moreno-Portillo, M., Bermejo-Martínez, L., Pichardo-Bahena, R., Baptista-González, H.A., Ponciano-Rodríguez, G., (...), Méndez-Sánchez, N. “Hepatic expression of ghrelin and adiponectin and their receptors in patients with nonalcoholic fatty liver disease”. Annals of Hepatology 7 (1), pp. 67-71, 2008.
  • Mendoza, M.G.A., Castillo-Henkel, C., Medina-Santillan, R., Jarillo Luna, R.A., Robles, H.V., Romo, E., Rios, A., Escalante, B. “Kidney damage after renal ablation is worsened in endothelial nitric oxide synthase (-/-) mice and improved by combined administration of L-arginine and antioxidants”. Nephrology 13 (3), pp. 218-227, 2008.
  • Rubio-Guerra, A.F., Vargas-Robles, H., Medina-Santillán, R., Escalante-Acosta, B.A. “Levels of soluble adhesion molecules among normotensive and hypertensive type 2 diabetic patients. [Niveles de moléculas de adhesión solubles en pacientes diabéticos tipo 2 normotensos e hipertensos]”. Gaceta Medica de Mexico 144 (1), pp. 11-14, 2008.
  • Jacques-Camarena O, González-Ortiz M, Martínez-Abundis E, López-Madrueño JF, Medina-Santillán R. “EFFECT OF VANADIUM ON INSULIN SENSITIVITY IN PATIENTS WITH IMPAIRED GLUCOSE TOLERANCE.” Ann Nutr Metab, 53 (3-4) 195-8. 2008.
  • Mixcoatl-Zecuatl T, Quinonez-Bastidas GN, Caram-Salas NL, Ambriz-Tututi M, Araiza-Saldana CI, Rocha-González HI, Medina-Santillán R, Reyes-García G, Granados-Soto V. “Synergistic antiallodynic interaction between gabapentin or carbamazepine and either benfotiamine or cyanocobalamin in neuropathic rats.” Methods Find Exp Clin Pharmacol. Jul-Aug;30(6):431-41. 2008.
  • Méndez-Sánchez, N., Chávez-Tapia, N.C., Zamora-Valdés, D., Medina-Santillán, R., Uribe, M. “Hepatobiliary diseases and insulin resistance”. Current Medicinal Chemistry 14 (18), pp. 1988-1999, 2007.
  • Hicks, J.J., Montes-Cortes, D.H., Cruz-Dominguez, M.P., Medina-Santillan, R., Olivares-Corichi, I.M. “Antioxidants decrease reperfusion induced arrhythmias in myocardial infarction with ST-elevation”. Frontiers in bioscience: a journal and virtual library 12, pp. 2029-2037, 2007.
  • Ble-Castillo, J.L., Cleva-Villanueva, G., Díaz-Zagoya, J.C., Medina-Santillán, R., Rubio-Arias, H.O., Méndez, J.D. “Effects of α-tocopherol on oxidative status and metabolic profile in overweight women”. International Journal of Environmental Research and Public Health 4 (4), pp. 260-267, 2007.
  • Flores-Murrieta FJ, Carrasco-Portugal Mdel C, Reyes-García G, Medina-Santillán R, Herrera JE. “Bioequivalence of two oral formulations of glyburide (glibenclamide).” Proc West Pharmacol Soc. 50:64-6. 2007.
  • Reyes-García G, Déciga-Campos M, Medina-Santillán R, Granados-Soto V. “Comparison of antinociceptive efficacy and gastroprotection between celecoxib and diclofenac plus misoprostol in rats.” Proc West Pharmacol Soc. 50:64-6. 2007.
  • Flores-Murrieta, F.J., Toledo, A., Carrasco-Portugal, M.del C., Reyes-García, G., Rodríguez-Silverio, J., Medina-Santillán, R., Herrera, J.E. “Comparative bioavailability of two oral formulations of ranitidine”. Biopharmaceutics and Drug Disposition, 27 (1), pp. 23-27. 2006.
  • Sánchez-Ramírez, G.M., Caram-Salas, N.L., Rocha-González, H.I., Vidal-Cantú, G.C., Medina-Santillán, R., Reyes-García, G., Granados-Soto, V. “Benfotiamine relieves inflammatory and neuropathic pain in rats”. European Journal of Pharmacology, 530 (1-2), pp. 48-53. 2006.
  • Villa-Caballero, L., Caballero-Solano, V., Chavarría-Gamboa, M., Linares-Lomeli, P., Torres-Valencia, E., Medina-Santillán, R., Palinkas, L.A. “Obesity and socioeconomic status in children of Tijuana”. American Journal of Preventive Medicine 30 (3), pp. 197-203. 2006.
  • Caram-Salas, N.L., Reyes-García, G., Medina-Santillán, R., Granados-Soto, V. “Thiamine and cyanocobalamin relieve neuropathic pain in rats: Synergy with dexamethasone”. Pharmacology 77 (2), pp. 53-62. 2006.
  • Carrasco-Portugal, M.D.C., Herrera, J.E., Reyes-García, G., Medina-Santillán, R., Flores-Murrieta, F.J. “Comparative bioavailability of two oral suspensions of naproxen sodium”. Arzneimittel-Forschung/Drug Research 56 (8), pp. 589-592. 2006.
  • Méndez-Sánchez, N., Chávez-Tapia, N.C., Medina-Santillán, R., Villa, A.R., Sánchez-Lara, K., Ponciano-Rodríguez, G., Ramos, M.H., Uribe, M. “The efficacy of adipokines and indices of metabolic syndrome as predictors of severe obesity-related hepatic steatosis”. Digestive Diseases and Sciences 51 (10), pp. 1716-1722. 2006.
  • Reyes-García, G., Medina-Santillán, R., Flores-Murrieta, F.J., Caram-Salas, N.L., Granados-Soto, V. “Analgesic effects of B vitamins: A review”. Current Topics in Pharmacology, 10 (1), pp. 1-31. 2006.
  • Arellano-Mendoza, M.G., Vargas-Robles, H., Castillo-Henkel, C., Reyes, G., Escalante-Acosta, B., Medina-Santillán, R. “Effects of supplementation with L-arginine, vitamins C and E, and ω-3 fatty acids on the development of kidney failure in mice”. Proceedings of the Western Pharmacology Society, 49, pp. 75-76. 2006.
  • Rodríguez-Silverio, J., Aguilar-Carrasco, J.C., Reyes-García, G., Medina-Santillán, R., Flores-Murrieta, F.J. “Antinociceptive and antiinflammatory effects of ketoprofen are potentiated by a vitamin B mixture in the rat”. Drug Development Research, 64 (1), pp. 66-70, 2005.
  • Flisser, A., Vázquez-Mendoza, A., Martínez-Ocaña, J., Gómez-Colín, E., Leyva, R.S., Medina-Santillán, R. “Short report: Evaluation of a self-detection tool for tapeworm carriers for use in public health”. American Journal of Tropical Medicine and Hygiene, 72 (5), pp. 510-512, 2005.
  • Del Carmen Carrasco-Portugal, M., Aguilar-Carrasco, J.C., Luján, M., Reyes-García, G., Medina-Santillán, R., Flores-Murrieta, F.J. “Further evidence for interethnic differences in the oral pharmacokinetics of meloxicam”. Clinical Drug Investigation, 25 (5), pp. 307-313. 2005.
  • Ble-Castillo, J.L., Carmona-Díaz, E., Méndez, J.D., Larios-Medina, F.J., Medina-Santillán, R., Cleva-Villanueva, G., Díaz-Zagoya, J.C. “Effect of α-tocopherol on the metabolic control and oxidative stress in female type 2 diabetics”. Biomedicine and Pharmacotherapy, 59 (6), pp. 290-295. 2005.
  • Olivares-Corichi, I.M., Ceballos, G., Medina-Santillan, R., Medina-Navarro, R., Guzman-Grenfell, A.M., Hicks, J.J. “Oxidation by reactive oxygen species (ROS) alters the structure of human insulin and decreases the insulin-dependent D-glucose-C14 utilization by human adipose tissue”. Frontiers in Bioscience, 10 (SUPPL. 3), pp. 3127-3131, 2005.
  • Medina-Santillán, R., Pérez-Flores, E., Mateos-García, E., Reyes-García, G., Granados-Soto, V., Flores-Murrieta, F.J. “A B-vitamin mixture reduces the requirements of diclofenac after tonsillectomy: A double-blind study”. Drug Development Research, 66 (1), pp. 36-39. 2005.
  • Espinosa-Larrañaga, F., Vejar-Jalaf, M., Medina-Santillán, R. “The importance of low serum levels of high-density lipoprotein cholesterol (HDL-C) as a cardiovascular risk factor”. Diabetes and Vascular Disease Research, 2 (SUPPL. 1), pp. S1-S8. 2005.
  • Terán-Rosales, F., Medina-Santillán, R., Reyes-García, G., Granados-Soto, V. “Synergistic antinociceptive interaction between acetaminophen or metamizol and B vitamins in the formalin test”. Drug Development Research, 66 (4), pp. 286-294. 2005.
  • Mixcoatl-Zecuatl, T., Medina-Santillán, R., Reyes-García, G., Vidal-Cantú, G.C., Granados-Soto, V. “Effect of K+ channel modulators on the antiallodynic effect of gabapentin”. European Journal of Pharmacology, 484 (2-3), pp. 201-208. 2004.
  • Granados-Soto, V., Terán-Rosales, F., Rocha-González, H.I., Reyes-García, G., Medina-Santillán, R., Rodríguez-Silverio, J., Flores-Murrieta, F.J. “Riboflavin reduces hyperalgesia and inflammation but not tactile allodynia in the rat”. European Journal of Pharmacology, 492 (1), pp. 35-40. 2004.
  • Caram-Salas, N.L., Medina-Santillán, R., Reyes-García, G., Granados-Soto, V. “Antinociceptive synergy between dexamethasone and the B vitamin complex in a neuropathic pain model in the rat”. Proceedings of the Western Pharmacology Society, 47, pp. 88-91. 2004.
  • Medina-Santillán, R., Morales-Franco, G., Espinoza-Raya, J., Granados-Soto, V., Reyes-García, G. “Treatment of diabetic neuropathic pain with gabapentin alone or combined with vitamin B complex. Preliminary results”. Proceedings of the Western Pharmacology Society, 47, pp. 109-112. 2004.
  • Medina-Santillán, R., Reyes-García, G., Rocha-González, H.I., Granados-Soto, V. “B vitamins increase the analgesic effect of ketorolac in the formalin test in the rat”. Proceedings of the Western Pharmacology Society, 47, pp. 95-99. 2004.
  • Reyes-García, G., Caram-Salas, N.L., Medina-Santillán, R., Granados-Soto, V. “Oral administration of B vitamins increases the antiallodynic effect of gabapentin in the rat”. Proceedings of the Western Pharmacology Society. 47, pp. 76-79. 2004.
  • Ortega-Varela, L.F., Herrera, J.E., Medina-Santillán, R., Reyes-García, G., Rocha-González, H.I., Granados-Soto, V. “Synergistic interaction between gabapentin and metamizol in the rat formalin test”. Proceedings of the Western Pharmacology Society. 47, pp. 80-83. 2004.
  • Hernández-Porras, M., Salmerón-Arteaga, G., Medina-Santillán, R. “Microbial resistance to antibiotics used to treat urinary tract infections in Mexican children”. Proceedings of the Western Pharmacology Society. 47, pp. 120-121. 2004.
  • Rocha-González, H.I., Terán-Rosales, F., Reyes-García, G., Medina-Santillán, R., Granados-Soto, V. “B vitamins increase the analgesic effect of diclofenac in the rat”. Proceedings of the Western Pharmacology Society. 47, pp. 84-87. 2004.
  • Granados-Soto, V., Sánchez-Ramírez, G., Rosas-De La Torre, M., Caram-Salas, N.L., Medina-Santillán, R., Reyes-García, G. “Effect of diclofenac on the antiallodynic activity of vitamin B12 in a neuropathic pain model in the rat”. Proceedings of the Western Pharmacology Society. 47, pp. 92-94. 2004.
  • Olivares-Corichi IM, Medina-Santillán R, Fernández del Valle-Laisequilla C, Alvarez P, Hicks-Gomez JJ. “Increase of human plasma antioxidant capacity with a novel formulation of antioxidants”. Proc West Pharmacol Soc.;46:45-7.
  • Flores-Murrieta FJ, Aguilar-Cota ME, Camacho A, Reyes-García G, Herrera JE, Medina-Santillán R. “Comparative bioavailability of two oral formulations.
  • manufactured in Mexico containing glyburide and metformin in diabetic patients”. Proc West Pharmacol Soc; 46:82-4. 2003.
  • Pérez-Flores E, Medina-Santillán R, Reyes-García G, Mateos-García E. “Combination of diclofenac plus B vitamins in acute pain after tonsillectomy: a pilot study”. Proc West Pharmacol Soc.;46:88-90. 2003.
  • Reyes-García G, Medina-Santillán R, Rocha-González HI, Granados-Soto V. “Synergistic interaction between spinal gabapentin and oral B vitamins in a neuropathic pain model”. Proc West Pharmacol Soc.;46:91-4. 2003.
  • Unzueta-Montoya A, Ordoñez-Toquero G, Medina-Santillán R. “Combined fixed doses therapy in systemic hypertension” Rev Invest Clin. Nov-Dec;55(6):635-41. Spanish. 2003.
  • Medina-Santillán R, Mateos-García E, Reyes-García G, Castañeda-Hernández G, Sotelo J. “Pharmacoeconomic analysis of the short scheme praziquantel in the treatment of neurocysticercosis”. Gac Med Mex. Mar-Apr;138(2):203-7. Review. Spanish. 200.
  • Medina Santillán R, Reyes-García G, Mateos-García E. “Metformin plus glyburide combination as initial therapy in type 2 diabetes: one month follow-up”. Proc West Pharmacol Soc.;45:137-8. 2002.
  • Medina Santillán R, Reyes-García G, Mateos-García E. “Metformin plus glyburide combination as therapy in failure to monotherapy in type 2 diabetic patients: one month follow-up”. Proc West Pharmacol Soc.;45:139-40. 2002.
  • Reyes-García G, Castillo-Henkel C, Medina-Santillán R, Terán-Rosales F, Granados-Soto V. “Mechanisms of analgesic action of B vitamins in formalin-induced inflammatory pain”. Proc West Pharmacol Soc.;45:144-6. 2002.
  • Reyes-García G, Medina-Santillán R, Terán-Rosales F, Castillo-Henkel C, Vidal-Cantú GC, Caram-Salas NL, Granados-Soto V. “B vitamins increase the anti-hyperalgesic effect of diclofenac in the rat”. Proc West Pharmacol Soc.;45:147-9. 2002.
  • González-Ortiz M, Medina-Santillán R, Martínez-Abundis E, von Drateln CR. “Effect of glycine on insulin secretion and action in healthy first-degree relatives of type 2 diabetes mellitus patients”. Horm Metab Res. Jun;33(6):358-60. 2001.
  • Reyes-García G, Medina-Santillán R, Terán-Rosales F, Castillo-Henkel C, Rodríguez-Silverio J, Torres-López JE, Ochoa-Cetina L, Medina-Tato DA, Granados-Soto V. “Analgesic effect of B vitamins in formalin-induced inflammatory pain”. Proc West Pharmacol Soc. 44:139-40. 2001.
  • Mateos-García E, Gaytán-Martínez J, Javier-González L, Castro-Escarpulli G, Reyes-García G, Medina-Santillán R, Casanova LJ, Fuentes-Allen JL. “Microbiological findings in soft tissue infections: concordance among three techniques of sampling”. Proc West Pharmacol Soc. 44:187-90. 2001.
  • Carrasco-Portugal MC, Granados-Soto V, Reyes-García G, Medina-Santillán R, Herrera JE, Flores-Murrieta FJ. “Multiple-dose pharmacokinetics of fluoxetine in healthy Mexican subjects”. Proc West Pharmacol Soc. 44:69-70. 2001.
  • Flores-Murrieta FJ, Aguilar-Cota ME, Granados-Soto V, Medina-Santillán R, Reyes-García G, Herrera JE. “Oral pharmacokinetics of cefaclor in Mexican subjects”. Proc West Pharmacol Soc. 44:71-2. 2001.
  • Sarti E, Schantz PM, Avila G, Ambrosio J, Medina-Santillán R, Flisser A. “Mass treatment against human taeniasis for the control of cysticercosis: a population-based intervention study”. Trans R Soc Trop Med Hyg. Jan-Feb;94(1):85-9. 2000.
  • Reyes-García G, Medina-Santillán R, Terán-Rosales F, Mateos-García E, Castillo-Henkel C. “Characterization of the potentiation of the antinociceptive effect of diclofenac by vitamin B complex in the rat”. J Pharmacol Toxicol Methods. Oct;42(2):73-7. 1999.
  • Medina Santillán R, Reyes García G, Herrera Benavente I, Mateos García E. “Efficacy of cefixime in the therapy of typhoid fever”. Proc West Pharmacol Soc. 43:65-6. No abstract available. 2000.
  • Medina Santillán R, Reyes García G, Sánchez Mejía JL, Mateos García E. “Dexamethasone alone versus dexamethasone plus complex B vitamins in the therapy of low back pain”. Proc West Pharmacol Soc. 43:69-70. 2000.
  • Unzueta Montoya A, Unzueta A Jr, Ordóñez Toquero G, Villasis Keever MA, Cocoletzi López J, Medina Santillán R. “Comparative study between bisoprolol and metoprolol, combined with hydrochlorothiazide, as antihypertensive therapy”. Arch Inst Cardiol Mex. Nov-Dec;70(6):589-95. Spanish. 2000.
  • Carvajal Sandoval G, Medina Santillán R, Juárez E, RamosMartínez G, Carvajal Juárez ME. “Effect of glycine on hemoglobin glycation in diabetic patients”. Proc West Pharmacol Soc. 42:31-2. 1999.
  • Medina Santillán R, Reyes García G, Mateos García E. “Prevention of gastroduodenal injury induced by NSAIDs with low-dose misoprostol”. Proc West Pharmacol Soc. 42:33-4. 1999.
  • Carvajal Sandoval G, Juárez E, Ramos Martínez G, Carvajal Juárez ME, Medina-Santillán R . “Inhibition of hemoglobin glycation with glycine in induced diabetes mellitus in rats”. Proc West Pharmacol Soc. 42:35-6. 1999.
  • Reyes García G, Medina Santillán R, Castillo Henkel E, Rodríguez Silverio J, Terán Rosales F, Mateos Garcìa E. “Analgesic effect of sodium diclofenac plus vitamin B complex in the PIFIR model”. Proc West Pharmacol Soc. 42:91-2. 1999.
  • Gerardo Reyes-García, Roberto Medina-Santillán, Flavio Terán-Rosales, Eduardo Mateos-García, Carlos Castillo-Henkel. “Characterization of the potentiation of the antinociceptive effect of diclofenac by vitamin B complex in the rat”. Journal of Pharmacological and Toxicological Methods, Volume 42, Issue 2, October Pages 73-77. 1999.
  • Pedrón Nuevo N, González-Unzaga M, Medina Santillan R. “Preventive treatment of primary dysmenorrhea with ibuprofen”. Ginecol Obstet Mex. Jun;66:248-52. Spanish. 1998.
  • Juliana G. De Liverant, Roberto Medina Santillan, Bulmaro Correa Meza, Citlali Marmolejo Saldivar. “Labelling dimercaptosuccinic acid (DMSA) and pyrophosphate with reduced 99mTc using stoichiometric quantities of stannous ion International Journal of Radiation Applications and Instrumentation”. Part C. Radiation Physics and Chemistry, Volume 38, Issue 2, Pages 274-275. 1991.
  • Medina-Santillán R, Vázquez-Savedra JA, Tanimoto M, Gordon F, García-Manzo NT. “Decrease in the serum concentration of triiodothyronine in patients with acute edematous pancreatitis”. Arch Invest Med (Mex). Jul-Sep;20(3):243-5. Spanish. 1989.
  • Schally AV, Medina-Santillan R, Colaluca J, Carter WH, Redding TW, Jones J, Altamirano-Bustamente P, Coy DH. “Inhibition of sham feeding-induced gastric secretion and serum hormonal responses by analogs of (pyro)Glu-His-Gly-OH”. Proc Soc Exp Biol Med. Jul;170(3):264-72. 1982.
  • Medina-Santillán R, Comaru-Schally AM, Schally AV. “Peptidergic appetite regulation”. Arch Invest Med (Mex). 13(2):117-22 passim. English, Spanish. 1982.
  • Flores-Esteva J, Medina-Santillán R, Berea-Domínguez H, Villalpando-Casas JJ, Martínez-Romero MA, Navarrete LR, Martin-Lombard ME. “Effect of diethylstilbestrol on plasma testosterone levels during 24 hours: study comparing doses of 1 and 5 mg. daily, and 1 mg. 3 times daily”. J Urol. Jun; 123 (6):887-9. 1980.
  • Gutiérrez Samperio C, Fuentes Gallegos H, Pérez Catzin F, Hernández López D, Mendoza Gómez S, Calderón Cruz CJ, Medina Santillán R. “Circulating gastrin in peptic ulcer and cancer of the stomach. Correlation with gastric chemistry”. Rev Gastroenterol Mex. May-Jun; 40 (3):126-31. Spanish. 1975